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1

Mechanism of microtubule stabilization by taccalonolide AJ

Wang, Yuxi, Yu, Yamei, Li, Guo-Bo, Li, Shu-Ang, Wu, Chengyong, Gigant, Benoît, Qin, Wenming, Chen, Hao, Wu, Yangping, Chen, Qiang, Yang, Jinliang

Journal:

Nature Communications

Year:

2017

Language:

english

File:

PDF, 2.09 MB

english, 2017

2

One- and two-photon absorption properties of a series of derived pyrazolines

Xin Zhou, Ai-Min Ren, Ji-Kang Feng, Xiao-Juan Liu, Guo-Bo Yang, Wen-Jing Tian

Journal:

Optical Materials

Year:

2004

Language:

english

File:

PDF, 474 KB

english, 2004

3

Discovery of novel mGluR1 antagonists: A multistep virtual screening approach based on an SVM model and a pharmacophore hypothesis significantly increases the hit rate and enrichment factor

Guo-Bo Li, Ling-Ling Yang, Shan Feng, Jian-Ping Zhou, Qi Huang, Huan-Zhang Xie, Lin-Li Li, Sheng-Yong Yang

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2011

Language:

english

File:

PDF, 653 KB

english, 2011

4

Association of amyloid precursor protein-binding protein, family B, member 1 with nicotine dependence in African and European American smokers

Guo-Bo Chen, Thomas J. Payne, Xiang-Yang Lou, Jennie Z. Ma, Jun Zhu, Ming D. Li

Journal:

Year:

2008

Language:

english

File:

PDF, 321 KB

english, 2008

5

ChemInform Abstract: Base-Mediated Tandem Reaction of α-Aryloxyacetophenones with Phosphonates: Selective Synthesis of Enol Phosphates.

Ren-Jie Song, Yan-Yun Liu, Ji-Cheng Wu, Ye-Xiang Xie, Guo-Bo Deng, Xu-Heng Yang, Yu Liu, Jin-Heng Li

Journal:

Year:

2012

File:

PDF, 46 KB

2012

6

Peniciside, a new triterpenoid glycoside, from the fungusPenicillium sp. 169

Xiao-Hong Yuan, Guo-Bo Xu, Wei-Lin Wu, Tao Yang, Guo-You Li

Journal:

Archives of Pharmacal Research

Year:

2012

Language:

english

File:

PDF, 521 KB

english, 2012

7

A Combinatorial Approach to Detecting Gene-Gene and Gene-Environment Interactions in Family Studies

Xiang-Yang Lou, Guo-Bo Chen, Lei Yan, Jennie Z. Ma, Jamie E. Mangold, Jun Zhu, Robert C. Elston, Ming D. Li

Journal:

The American Journal of Human Genetics

Year:

2008

Language:

english

File:

PDF, 350 KB

english, 2008

8

A Generalized Combinatorial Approach for Detecting Gene-by-Gene and Gene-by-Environment Interactions with Application to Nicotine Dependence

Xiang-Yang Lou, Guo-Bo Chen, Lei Yan, Jennie Z. Ma, Jun Zhu, Robert C. Elston, Ming D. Li

Journal:

The American Journal of Human Genetics

Year:

2007

Language:

english

File:

PDF, 580 KB

english, 2007

9

Chaetoconvosins A and B, Alkaloids with New Skeleton from Fungus Chaetomium convolutum

Xu, Guo-Bo, Li, Li-Mei, Yang, Tao, Zhang, Guo-Lin, Li, Guo-You

Journal:

Organic Letters

Year:

2012

Language:

english

File:

PDF, 422 KB

english, 2012

10

ID-Score: A New Empirical Scoring Function Based on a Comprehensive Set of Descriptors Related to Protein–Ligand Interactions

Li, Guo-Bo, Yang, Ling-Ling, Wang, Wen-Jing, Li, Lin-Li, Yang, Sheng-Yong

Journal:

Journal of Chemical Information and Modeling

Year:

2013

Language:

english

File:

PDF, 826 KB

english, 2013

11

Discovery of N6-phenyl-1H-pyrazolo[3,4-d]pyrimidine-3,6-diamine derivatives as novel CK1 inhibitors using common-feature pharmacophore model based virtual screening and hit-to-lead optimization

Yang, Ling-Ling, Li, Guo-Bo, Yan, Heng-Xiu, Sun, Qi-Zheng, Ma, Shuang, Ji, Pan, Wang, Ze-Rong, Feng, Shan, Zou, Jun, Yang, Sheng-Yong

Journal:

European Journal of Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 1.25 MB

english, 2012

12

Structure–Activity Relationship Studies of Pyrazolo[3,4- d ]pyrimidine Derivatives Leading to the Discovery of a Novel Multikinase Inhibitor That Potently Inhibits FLT3 and VEGFR2 and Evaluation of Its Activity against Acute Myeloid Leukemia in Vitro and in Vivo

Yang, Ling-Ling, Li, Guo-Bo, Ma, Shuang, Zou, Chan, Zhou, Shu, Sun, Qi-Zheng, Cheng, Chuan, Chen, Xin, Wang, Li-Jiao, Feng, Shan, Li, Lin-Li, Yang, Sheng-Yong

Journal:

Journal of Medicinal Chemistry

Year:

2013

Language:

english

File:

PDF, 4.87 MB

english, 2013

13

Practical and Theoretical Considerations in Study Design for Detecting Gene-Gene Interactions Using MDR and GMDR Approaches

Chen, Guo-Bo, Xu, Yi, Xu, Hai-Ming, Li, Ming D., Zhu, Jun, Lou, Xiang-Yang, Mailund, Thomas

Journal:

Year:

2011

Language:

english

File:

PDF, 858 KB

english, 2011

14

Isochaetomium A2, a new bis(naphthodihydropyran-4-one) with antimicrobial and immunological activities from fungusChaetomium microcephalum

Guo-Bo Xu, Tao Yang, Jin-Ku Bao, Dong-Mei Fang…

Journal:

Archives of Pharmacal Research

Year:

2014

Language:

english

File:

PDF, 273 KB

english, 2014

15

A combined molecular docking-based and pharmacophore-based target prediction strategy with a probabilistic fusion method for target ranking

Li, Guo-Bo, Yang, Ling-Ling, Xu, Yong, Wang, Wen-Jing, Li, Lin-Li, Yang, Sheng-Yong

Journal:

Journal of Molecular Graphics and Modelling

Year:

2013

Language:

english

File:

PDF, 1.92 MB

english, 2013

16

A unified GMDR method for detecting gene–gene interactions in family and unrelated samples with application to nicotine dependence

Chen, Guo-Bo, Liu, Nianjun, Klimentidis, Yann C., Zhu, Xiaofeng, Zhi, Degui, Wang, Xujing, Lou, Xiang-Yang

Journal:

Year:

2014

Language:

english

File:

PDF, 837 KB

english, 2014

17

THE VIRCHOW MEMORIAL.

He, Zhi-Yao, Wei, Xia-Wei, Luo, Min, Luo, Shun-Tao, Yang, Yang, Yu, Yi-Yi, Chen, Yan, Ma, Cui-Cui, Liang, Xiao, Guo, Fu-Chun, Ye, Ting-Hong, Shi, Hua-Shan, Shen, Guo-Bo, Wang, Wei, Gong, Feng-Ming, He

Journal:

Year:

1902

Language:

english

File:

PDF, 176 KB

english, 1902

18

Folate-linked lipoplexes for short hairpin RNA targeting claudin-3 delivery in ovarian cancer xenografts

He, Zhi-Yao, Wei, Xia-Wei, Luo, Min, Luo, Shun-Tao, Yang, Yang, Yu, Yi-Yi, Chen, Yan, Ma, Cui-Cui, Liang, Xiao, Guo, Fu-Chun, Ye, Ting-Hong, Shi, Hua-Shan, Shen, Guo-Bo, Wang, Wei, Gong, Feng-Ming, He

Journal:

Journal of Controlled Release

Year:

2013

Language:

english

File:

PDF, 2.86 MB

english, 2013

19

Estimation of SNP Heritability from Dense Genotype Data

Lee, S. Hong, Yang, Jian, Chen, Guo-Bo, Ripke, Stephan, Stahl, Eli A., Hultman, Christina M., Sklar, Pamela, Visscher, Peter M., Sullivan, Patrick F., Goddard, Michael E., Wray, Naomi R.

Journal:

The American Journal of Human Genetics

Year:

2013

Language:

english

File:

PDF, 107 KB

english, 2013

20

A prediction model of drug-induced ototoxicity developed by an optimal support vector machine (SVM) method

Zhou, Shu, Li, Guo-Bo, Huang, Lu-Yi, Xie, Huan-Zhang, Zhao, Ying-Lan, Chen, Yu-Zong, Li, Lin-Li, Yang, Sheng-Yong

Journal:

Computers in Biology and Medicine

Year:

2014

Language:

english

File:

PDF, 251 KB

english, 2014

21

Accumulation of FLT3+CD11c+dendritic cells in psoriatic lesions and the anti-psoriatic effect of a selective FLT3 inhibitor

Yan, Heng-Xiu, Li, Wei-Wei, Zhang, Yan, Wei, Xia-Wei, Fu, Li-Xin, Shen, Guo-Bo, Yin, Tao, Li, Xiu-Ying, Shi, Hua-Shan, Wan, Yang, Zhang, Qing-Yin, Li, Jiong, Yang, Sheng-Yong, Wei, Yu-Quan

Journal:

Immunologic Research

Year:

2014

Language:

english

File:

PDF, 4.81 MB

english, 2014

22

New Orsellinic Acid Esters from Fungus Chaetomium globosporum

Xu, Guo-Bo, Wang, Ni-Ni, Bao, Jin-Ku, Yang, Tao, Li, Guo-You

Journal:

Helvetica Chimica Acta

Year:

2014

Language:

english

File:

PDF, 300 KB

english, 2014

23

Virtual screening in small molecule discovery for epigenetic targets

Li, Guo-Bo, Yang, Ling-Ling, Yuan, Yiming, Zou, Jun, Cao, Yu, Yang, Sheng-Yong, Xiang, Rong, Xiang, Mingli

Journal:

Year:

2015

Language:

english

File:

PDF, 802 KB

english, 2015

24

Vitrification of Mouse Embryos at Various Stages by Open-Pulled Straw (OPS) Method

Zhou, Guang-Bin, Zhu, Shi-En, Hou, Yun-Peng, Jin, Fang, Yang, Qi-En, Yang, Zhong-Qiang, Quan, Guo-Bo, Tan, Hong-Ming

Journal:

Animal Biotechnology

Year:

2005

Language:

english

File:

PDF, 88 KB

english, 2005

25

Metal-free nitrative cyclization of N-aryl imines with tert-butyl nitrite: dehydrogenative access to 3-nitroindoles

Deng, Guo-Bo, Zhang, Jia-Ling, Liu, Yan-Yun, Liu, Bang, Yang, Xu-Heng, Li, Jin-Heng

Journal:

Chemical Communications

Year:

2015

Language:

english

File:

PDF, 698 KB

english, 2015

26

SC-535, a Novel Oral Multikinase Inhibitor, Showed Potent Antitumor Activity in Human Melanoma Models

Chen, Xin, Ji, Pan, Yang, Hui-Wen, Yang, Ling-Ling, Zhou, Shu, Zhong, Lei, Ma, Shuang, Fu, Xiao-Yu, Zhou, Chan, Li, Guo-Bo, Zheng, Ming-Wu, Wei, Yu-Quan, Yang, Sheng-Yong

Journal:

Cellular Physiology and Biochemistry

Year:

2013

Language:

english

File:

PDF, 1.73 MB

english, 2013

27

LEADOPT: An automatic tool for structure-based lead optimization, and its application in structural optimizations of VEGFR2 and SYK inhibitors

Li, Guo-Bo, Ji, Sen, Yang, Ling-Ling, Zhang, Rong-Jie, Chen, Kai, Zhong, Lei, Ma, Shuang, Yang, Sheng-Yong

Journal:

European Journal of Medicinal Chemistry

Year:

2015

Language:

english

File:

PDF, 4.51 MB

english, 2015

28

Design, Synthesis, and Structure–Activity Relationship Studies of 3-(Phenylethynyl)-1 H -pyrazolo[3,4- d ]pyrimidin-4-amine Derivatives as a New Class of Src Inhibitors with Potent Activities in Models of Triple Negative Breast Cancer

Zhang, Chun-Hui, Zheng, Ming-Wu, Li, Ya-Ping, Lin, Xing-Dong, Huang, Mei, Zhong, Lei, Li, Guo-Bo, Zhang, Rong-Jie, Lin, Wan-Ting, Jiao, Yan, Wu, Xiao-Ai, Yang, Jiao, Xiang, Rong, Chen, Li-Juan, Zhao,

Journal:

Journal of Medicinal Chemistry

Year:

2015

Language:

english

File:

PDF, 952 KB

english, 2015

29

Mixed Model with Correction for Case-Control Ascertainment Increases Association Power

Hayeck, Tristan J., Zaitlen, Noah A., Loh, Po-Ru, Vilhjalmsson, Bjarni, Pollack, Samuela, Gusev, Alexander, Yang, Jian, Chen, Guo-Bo, Goddard, Michael E., Visscher, Peter M., Patterson, Nick, Price, A

Journal:

The American Journal of Human Genetics

Year:

2015

Language:

english

File:

PDF, 204 KB

english, 2015

30

4-(4-Nitrobenzyl)morpholine

Yang, Ling-Ling, Zheng, Ren-Lin, Li, Guo-Bo, Sun, Qi-Zheng, Xie, Yong-Mei

Journal:

Acta Crystallographica Section E Structure Reports Online

Year:

2011

Language:

english

File:

PDF, 748 KB

english, 2011

31

Indole Alkaloids from Chaetomium globosum

Xu, Guo-Bo, He, Gu, Bai, Huan-Huan, Yang, Tao, Zhang, Guo-Lin, Wu, Lin-Wei, Li, Guo-You

Journal:

Journal of Natural Products

Year:

2015

Language:

english

File:

PDF, 1.21 MB

english, 2015

32

Statistical Power to Detect Genetic (Co)Variance of Complex Traits Using SNP Data in Unrelated Samples

Visscher, Peter M., Hemani, Gibran, Vinkhuyzen, Anna A. E., Chen, Guo-Bo, Lee, Sang Hong, Wray, Naomi R., Goddard, Michael E., Yang, Jian, Barsh, Gregory S.

Journal:

Year:

2014

Language:

english

File:

PDF, 554 KB

english, 2014

33

Enhanced electron injection in laser-driven bubble acceleration by ultra-intense laser irradiating foil-gas targets

Zhang, Guo-Bo, Ma, Yan-Yun, Xu, Han, Hafz, Nasr A. M., Yang, Xiao-Hu, Chen, Min, Yu, Tong-Pu, Zou, De-Bin, Liu, Jian-Xun, Yan, Jian-Feng, Zhuo, Hong-Bin, Gan, Long-Fei, Tian, Li-Chao, Shao, Fu-Qiu, Yi

Journal:

Physics of Plasmas

Year:

2015

Language:

english

File:

PDF, 1.76 MB

english, 2015

34

A pyrane based fluorescence probe for noninvasive prediction of cerebral β-amyloid fibrils

Cheng, Yan, Zhu, Bi-yue, Li, Xue, Li, Guo-bo, Yang, Sheng-yong, Zhang, Zhi-rong

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2015

Language:

english

File:

PDF, 1.20 MB

english, 2015

35

Base-Mediated Tandem Reaction of α-Aryloxyacetophenones with Phosphonates: Selective Synthesis of Enol Phosphates

Song, Ren-Jie, Liu, Yan-Yun, Wu, Ji-Cheng, Xie, Ye-Xiang, Deng, Guo-Bo, Yang, Xu-Heng, Liu, Yu, Li, Jin-Heng

Journal:

Year:

2012

Language:

english

File:

PDF, 160 KB

english, 2012

36

Synthesis and evaluation of styrylpyran fluorophores for noninvasive detection of cerebral β-amyloid deposits

Zhu, Bi-yue, Cheng, Yan, Li, Guo-bo, Yang, Sheng-yong, Zhang, Zhi-rong

Journal:

Bioorganic & Medicinal Chemistry

Year:

2016

Language:

english

File:

PDF, 2.41 MB

english, 2016

37

Dehydrogenative [2 + 2 + 1] Heteroannulation Using a Methyl Group as a One-Carbon Unit: Access to Pyrazolo[3,4- c ]quinolines

Deng, Guo-Bo, Li, Hai-Bing, Yang, Xu-Heng, Song, Ren-Jie, Hu, Ming, Li, Jin-Heng

Journal:

Organic Letters

Year:

2016

Language:

english

File:

PDF, 751 KB

english, 2016

38

Adsorption and Enrichment of Alkalids from Areca Nut by Means of Macroporous Resins

Ding, Yan, Yang, Xiao-ming, Pan, Guo-bo, Ma, Hai-le, Liu, Wei-min

Journal:

Adsorption Science and Technology

Year:

2012

Language:

english

File:

PDF, 208 KB

english, 2012

39

Identification of new p300 histone acetyltransferase inhibitors from natural products by a customized virtual screening method

Li, Guo-Bo, Huang, Lu-Yi, Li, Hui, Ji, Sen, Li, Lin-Li, Yang, Sheng-Yong

Journal:

Year:

2016

Language:

english

File:

PDF, 533 KB

english, 2016

40

ChemInform Abstract: New Orsellinic Acid Esters from Fungus Chaetomium globosporum.

Xu, Guo-Bo, Wang, Ni-Ni, Bao, Jin-Ku, Yang, Tao, Li, Guo-You

Journal:

Year:

2014

File:

PDF, 25 KB

2014

41

An integrated molecular docking and rescoring method for predicting the sensitivity spectrum of various serine hydrolases to organophosphorus pesticides

Yang, Ling-Ling, Yang, Xiao, Li, Guo-Bo, Fan, Kai-Ge, Yin, Peng-Fei, Chen, Xiang-Gui

Journal:

Journal of the Science of Food and Agriculture

Year:

2016

Language:

english

File:

PDF, 1.29 MB

english, 2016

42

ChemInform Abstract: Metal-Free Nitrative Cyclization of N-Aryl Imines with tert-Butyl Nitrite: Dehydrogenative Access to 3-Nitroindoles.

Deng, Guo-Bo, Zhang, Jia-Ling, Liu, Yan-Yun, Liu, Bang, Yang, Xu-Heng, Li, Jin-Heng

Journal:

Year:

2015

File:

PDF, 29 KB

2015

43

Drug Discovery against Psoriasis: Identification of a New Potent FMS-like Tyrosine Kinase 3 (FLT3) Inhibitor, 1-(4-((1 H -Pyrazolo[3,4- d ]pyrimidin-4-yl)oxy)-3-fluorophenyl)-3-(5-( tert -butyl)isoxazol-3-yl)urea, That Showed Potent Activity in a Psoriatic Animal Model

Li, Guo-Bo, Ma, Shuang, Yang, Ling-Ling, Ji, Sen, Fang, Zhen, Zhang, Guo, Wang, Li-Jiao, Zhong, Jie-Min, Xiong, Yu, Wang, Jiang-Hong, Huang, Shen-Zhen, Li, Lin-Li, Xiang, Rong, Niu, Dawen, Chen, Ying-

Journal:

Journal of Medicinal Chemistry

Year:

2016

Language:

english

File:

PDF, 1.95 MB

english, 2016

44

Treatment of dextran sodium sulfate-induced experimental colitis by adoptive transfer of peritoneal cells

Liu, Ting, Ren, Jun, Wang, Wei, Wei, Xia-wei, Shen, Guo-bo, Liu, Yan-tong, Luo, Min, Xu, Guang-chao, Shao, Bin, Deng, Sen-yi, He, Zhi-yao, Liang, Xiao, Liu, Yu, Wen, Yan-Zhu, Xiang, Rong, Yang, Li, De

Journal:

Scientific Reports

Year:

2015

Language:

english

File:

PDF, 2.54 MB

english, 2015

45

NMR-filtered virtual screening leads to non-metal chelating metallo-β-lactamase inhibitors

Li, Guo-Bo, Abboud, Martine I., Brem, Jürgen, Someya, Hidenori, Lohans, Christopher T., Yang, Sheng-Yong, Spencer, James, Wareham, David W., McDonough, Michael A., Schofield, Christopher J.

Journal:

Chemical Science

Year:

2017

Language:

english

File:

PDF, 1.08 MB

english, 2017

46

ChemInform Abstract: Dehydrogenative [2 + 2 + 1] Heteroannulation Using a Methyl Group as a One-Carbon Unit: Access to Pyrazolo[3,4-c]quinolines.

Deng, Guo-Bo, Li, Hai-Bing, Yang, Xu-Heng, Song, Ren-Jie, Hu, Ming, Li, Jin-Heng

Journal:

Year:

2016

File:

PDF, 29 KB

2016

47

Enhanced electron–positron pair production by ultra intense laser irradiating a compound target

Liu, Jian-Xun, Ma, Yan-Yun, Yu, Tong-Pu, Zhao, Jun, Yang, Xiao-Hu, Gan, Long-Fei, Zhang, Guo-Bo, Zhao, Yuan, Zhang, Shi-Jie, Liu, Jin-Jin, Zhuo, Hong-Bin, Shao, Fu-Qiu, Kawata, Shigeo

Journal:

Plasma Physics and Controlled Fusion

Year:

2016

Language:

english

File:

PDF, 3.82 MB

english, 2016

48

Dense pair plasma generation by two laser pulses colliding in a cylinder channel

Liu, Jian-Xun, Ma, Yan-Yun, Yu, Tong-Pu, Zhao, Jun, Yang, Xiao-Hu, Zou, De-Bin, Zhang, Guo-Bo, Zhao, Yuan, Yang, Jing-Kang, Li, Han-Zhen, Zhuo, Hong-Bin, Shao, Fu-Qiu, Kawata, Shigeo

Journal:

Chinese Physics B

Year:

2017

Language:

english

File:

PDF, 2.13 MB

english, 2017

49

Crystallographic Analyses of Isoquinoline Complexes Reveal a New Mode of Metallo-β-Lactamase Inhibition

Li, Guo-Bo, Brem, Jurgen, Lesniak, Robert, Abboud, Martine I. I, Lohans, Christopher T, Clifton, Ian J, Yang, Sheng-Yong, Jimenez-Castellanos, Juan-Carlos, Avison, Matthew B, Spencer, James, McDonough

Journal:

Chemical Communications

Year:

2017

Language:

english

File:

PDF, 1.06 MB

english, 2017

50

IFPTarget: A Customized Virtual Target Identification Method Based on Protein-Ligand Interaction Fingerprinting Analyses

Li, Guo-Bo, Yu, Zhu-Jun, Liu, Sha, Huang, Lu-Yi, Yang, Ling-Ling, Lohans, Christopher Thomas, Yang, Sheng-Yong

Journal:

Journal of Chemical Information and Modeling

Year:

2017

Language:

english

File:

PDF, 1.99 MB

english, 2017